Frequently Asked Questions

Looking for pet, equine or general Integricare information? Get answers to all of the commonly asked questions about our products, their ingredients, and dosage. Toggle through the frequently asked questions tabs to find the information that you’re looking for.

Supplier Since 1999
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Looking for pet, equine or general Integricare information? Toggle through the frequently asked questions tabs to find the information that you’re looking for.

Why is supplementation important?

Most pet owners don’t think about joint supplements until they notice signs of pain or decreased mobility. It is estimated that one in five dogs one year and older already have some degree of osteoarthritis and 90 percent of older dogs have osteoarthritis. Moreover, 61% of cats over the age of 6 have osteoarthritis and 82% of cats over 14 years of age have the condition. All animals will eventually experience some degree of joint degeneration. Osteoarthritis can occur in one or more joints. However, pets are very good at hiding pain and the onset of osteoarthritis is slow. By the time you notice the signs, your pet is already experiencing joint degeneration. In fact, deterioration of joint cartilage occurs naturally as the body ages because the body’s ability to produce glucosamine, chondroitin, and MSM slows down.

Supplementing young dogs is important to ensure the joints and bones develop properly. Hip dysplasia is often the result of improper development of the joints during maturation. A proactive approach can decrease the likelihood of hip and joint complications in a pet’s later years. Using TRI-ACTA Regular Strength on a daily basis at a young age will prevent or significantly reduce the effects and severity of joint deterioration, osteoarthritis, and dysplasia as an animal ages.

Animals that are at later stages in the progression of osteoarthritis or hip dysplasia or have experienced injury, trauma, or surgery require higher levels of glucosamine, chondroitin, MSM, and hyaluronic acid than their bodies can produce. TRI-ACTA and TRI-ACTA H.A. provide therapeutic levels of these ingredients to ensure pain is reduced and the cartilage matrix is being repaired.

My dog food contains Glucosamine. Do I need to supplement?

It certainly won’t hurt using a pet food with glucosamine. However, in order for glucosamine to have any therapeutic or preventive value, your pet requires on average, roughly 18-20 mg of glucosamine per pound of body weight. This means a 50-pound dog needs about 900-1000 mg of glucosamine daily. The amount of glucosamine in pet foods is significantly less than what is actually needed. You would need to feed several kilos of kibble per day and still wouldn’t get close to the minimal required level of glucosamine. A comprehensive and complete approach to joint supplementation with TRI-ACTA is a proactive approach that will ensure the deterioration of your dog’s joints is prevented or significantly reduced. For dogs that already exhibit signs of joint discomfort, TRI-ACTA H.A. will treat the symptoms, repair damaged cartilage, and work toward preventing cartilage from further deteriorating.

My dog is using NSAIDs. Can I use TRI-ACTA?

TRI-ACTA can be used in conjunction with NSAIDs (non-steroidal anti-inflammatory drugs) or as an alternative.

NSAIDs are often prescribed to treat pain associated with conditions such as arthritis, degenerative joint disease, and dysplasia. While NSAIDs reduce pain and inflammation, they do not actively repair the cartilage matrix, including proteoglycans and collagen. Because they mask pain without addressing the cause, animals can easily further damage their joints worsening their condition. Additionally, there are several side effects of NSAIDs including stomach ulceration, intestinal bleeding, vomiting, loss of appetite, and loss of kidney function/failure.

Some of these side effects can assume life threatening proportions. NSAIDs work by blocking the production of prostaglandins (hormonelike substances that can trigger inflammation). But blocking these inflammation-promoting prostaglandins is also the source of NSAIDs side effects. Prostaglandins play other roles in the body. For example, they are needed to control the secretion of gastric juices and mucus that serve as stomach lining. This is why NSAIDs are linked to ulcers and even life threatening gastric bleeding. Additionally, although NSAIDs suppress symptoms, they also speed up the progression of the disease.

TRI-ACTA is a safer, more effective alternative with none of the side effects. TRI-ACTA not only reduces inflammation and pain, it also actively repairs the cartilage and prevents further breakdown halting the progress of the disease. If your vet has prescribed NSAIDs for pain relief, you could use TRI-ACTA in conjunction with it, using the NSAIDs only as needed.

Should I use TRI-ACTA supplements in conjunction with NSAIDs, injectables or other medications?

Yes, TRI-ACTA supplements can compliment the use of other mobility and pain medications. Many of our customers have actually been able to lengthen the period of time in-between administering NSAIDs, injectables and other medications by having their horse on a daily serving of TRI-ACTA. Keep in mind, prolonged administration of NSAIDs suppresses prostaglandin production in the gastrointestinal system and has been linked to the development of gastric ulcers.

Why is TRI-ACTA more effective than using pure Glucosamine or MSM?

Scientific studies consistently indicate that utilizing a blended formula of complimentary ingredients provide a significant advantage in supporting joint health and mobility than individual ingredients alone. With TRI-ACTA products, your horse receives a daily therapeutic dose of two types of glucosamine, chondroitin, MSM, and hyaluronic acid. Specifically formulated to work together, TRI-ACTA’s blended formula addresses joint health and mobility from all angles to deliver better results than single components alone.

Is TRI-ACTA safe for competitions and FEI legal?

Yes, TRI-ACTA and TRI-ACTA H.A. are completely safe and legal for FEI (International Federation for Equestrian Sports) competition. The ingredients and manufacturing processes for TRI-ACTA products abide by all regulatory guidelines as indicated by the FEI. TRI-ACTA and TRI-ACTA H.A. are also designated as a Veterinary Health Product (VHP) by Health Canada. Top level riders and trainers rely on TRI-ACTA during competition and racing because of the purity of ingredients and stringent quality control measures.

My horse is a picky-eater. Is TRI-ACTA palatable to horses?

Yes. Because TRI-ACTA’s daily serving size is so small compared to other supplements, your horse won’t notice when you include TRI-ACTA in their daily grain. TRI-ACTA contains no filler or artificial flavoring which can be attributed to the small serving size. At just 20-22g per daily serving, your horse won’t be able to detect TRI-ACTA when mixed in with grain.

Should I give my horse the suggested loading dose when starting TRI-ACTA?

Yes. As with any supplement, it is essential to follow the label instructions and administer to your horse accordingly. TRI-ACTA’s loading dose is to administer 2 scoops per day for 10 days. By administering the 10 day loading dose, the optimal levels of key ingredients are able to be reached within the equine body more quickly and effectively. When optimal levels of TRI-ACTA ingredients are reached in the body, the bio-accumulation, efficacy, and therapeutic value of the product can be maximized and begin working to restore and maintain your horse’s joint health and mobility.

I’m already using another joint supplement as part of my horse’s overall maintenance regimen. Why should I consider switching to TRI-ACTA?

There are many reasons that TRI-ACTA stands apart and is proven more effective than other joint and mobility supplements on the market. The main advantage to using TRI-ACTA is that our supplements contain no filler. Having no filler in our products allows for a very competitive cost per serving as well as ensures a pure and safe product with no risk of adverse side effects.

TRI-ACTA has a three year shelf life which is a testament to the purity and stability of our product. TRI-ACTA is also the only joint product on the market to use two types of glucosamine for dual benefit*. We also include chondroitin in our supplements, which studies show works synergistically with glucosamines to enhance the efficacy of both ingredients.

TRI-ACTA only includes ingredients that resemble what is naturally produced in the equine body. As such, it is a natural supplement and is highly bioavailable. We also source all our ingredients within Canada at pharmaceutical grade. TRI-ACTA is designated a Veterinary Health Product (VHP) by Health Canada, indicating that it meets health, safety, and quality assurance standards.

How soon should I expect to see results when starting my horse on TRI-ACTA?

Every horse is different. Depending on whether you start your horse on the suggested loading dose or not, you should expect to see positive results within 10-14 days. If you follow the loading dose instructions, you can expect to see positive results at the end of the 10 day loading dose period. Keep in mind that results will vary depending on the age and workload of the horse, as well as if they’re on NSAID medications. The bioavailability of TRI-ACTA may also be compromised if your horse is on omeprazole or another medication that limits the absorption of nutrients via the gut and/or limits the excretion of stomach acid.

Should I use TRI-ACTA every day, or only when my horse is competing or training harder?

TRI-ACTA will deliver consistent, positive results when used on a regular, continuous basis. As our label indicates, we recommend giving your horse one daily serving of TRI-ACTA after completion of the initial 10-day loading dose period. Bio-accumulation will occur with daily, continuous use of TRI-ACTA, providing consistent joint and mobility support for your equine partner.

I am currently feeding my animal another joint supplement. Why should I switch??

TRI-ACTA formulas provide therapeutic levels of active ingredients. Many other brands are only subtherapeutic and contain 50-90% inactive ingredients. Because TRI-ACTA products are concentrates, the dosages are small, and the containers are extremely economical. TRI-ACTA uses pharmaceutical grade ingredients and is validated and regulated by a LRVHP number (Health Canada Approved). This means the contents and quality is regulated. Consumers can feel confident that they are getting what is stated on the label.

Which formula do I choose?

We recommend the TRI-ACTA H.A. formula for mature animals and/or animals with osteoarthritis, hip dysplasia, recovering from surgery, or experiencing significant pain and/or immobility. TRI-ACTA H.A. can also be used as a preventative supplement for very active dogs and sporting dogs under a heavier workload.

The maintenance formula can also be used for recovery/therapeutic purposes, although it is more commonly used as a preventative approach for optimal joint health and for younger animals that have not already shown signs of decreased mobility or are just starting to.

What is TRI-ACTA and TRI-ACTA H.A.?

TRI-ACTA and TRI-ACTA H.A. are premium supplements for the prevention and treatment of problems associated with joints, bone, muscles, tendons, and ligaments.

TRI-ACTA is the maintenance formula and consists of Glucosamine, Chondroitin, MSM.

TRI-ACTA H.A. is the maximum strength formula, with the added benefit of Hyaluronic Acid.

What makes TRI-ACTA products better?

TRI-ACTA products contain 100% active ingredients – No Filler! The formulas use pure and natural forms of glucosamine, chondroitin, MSM, and Hyaluronic Acid at therapeutic dosages. Because they are concentrates the dosages are small. Many other joint supplements contain between 50-90% inactive ingredients and only use sub-therapeutic levels of active ingredients. TRI-ACTA products use both Sulphate and Hydrochloride forms of glucosamine to ensure all benefits of glucosamine are available. Additionally, the ingredients are pharmaceutical grade and backed with certificates of analysis. All TRI-ACTA products have Health Canada Low Risk Veterinary Health Product Numbers (LRVHP). To date, most pet supplements are not LRVHP approved. There are no adverse side effects with TRI-ACTA products.

What do Glucosamine, Chondroitin, MSM and Hyaluronic Acid do?

Hyaluronic Acid

Hyaluronic Acid is a naturally occurring substance found in connective tissue such as cartilage, bone, skin, and body fluids. Hyaluronic Acid increases the viscosity and supply of synovial fluid (joint fluid) in articulating joints. Through joint lubrication, nutrients are swept into the cartilage and toxins are carried out. Hyaluronic Acid keeps cartilage strong and flexible and provides a shock absorbing effect.


Glucosamine is a naturally occurring substance in a horse’s body and is a fundamental building block necessary for the synthesis of key joint structures, including cartilage and joint fluid. It provides structure to the bone and cartilage as well as other tissues and is one of the biological chemicals that form the major cushioning ingredients of a joint’s synovial fluid.
Glucosamine leads to the repair and reproduction of healthy cartilage by stimulating the production of glycosaminoglycans (GAGs) and proteoglycans, core components of cartilage. Glucosamine is bioavailable and when used as a dietary supplement, it is absorbed daily, lubricating and nourishing the cartilage cells and in turn producing new healthy cartilage cells.

Chondroitin Sulphate

Chondroitin sulfate consists of glycosaminoglycans (GAGs), glucuronic acid and galactosamine. The structure of the cartilage matrix allows chondroitin to contribute to joint lubrication by helping to sweep nutrients into the cartilage. The presence of chondroitin, along with collagen enables the cartilage to provide a tough, wear-resistant, weight-bearing surface with shock absorbing effects. Chondroitin also inhibits and neutralizes destructive enzymes in the joint, preventing the breakdown of cartilage. Chondroitin is bioavailable and safely alleviates symptoms of degenerative joint disease.

MSM (Methylsulfonylmethane)

MSM is a healthy and safe dietary supplement that provides sulfur, which is required to utilize vitamins and amino acids needed for healthy cartilage, ligaments, tendons, heart valves and all connective tissue. It helps the body form a strong collagen matrix helps animals move more freely and easily, particularly in cases of soft tissue injury. MSM also relieves swelling, inflammation and pain.

How do Glucosamine and Chondroitin work?

Glucosamine provides a building block of cartilage. Cartilage consists of several different cells, one of which is chondrocytes. Chondrocytes are responsible for synthesizing new cartilage. Through normal wear, cartilage is constantly being broken down and replaced.

Glucosamine provides the building blocks to synthesize new cartilage. It is necessary for the production of a substance called glycosaminoglycans. The glycosaminoglycans are combined with hyaluronic acid to make the substance proteoglycans. The proteoglycans and collagen are the main structures of cartilage.

Chondroitin is also necessary for the synthesis of glycosaminoglycans. But more importantly it inhibits and neutralizes destructive enzymes in the joint. While destructive enzymes are always present in the joint to some degree, when injury or abnormal wear occurs, there is an increased presence and cartilage destruction is accelerated.

Why do TRI-ACTA products contain 2 types of Glucosamine?

Research shows that both Glucosamine Sulfate and Glucosamine Hydrochloride are extremely effective products for joint care. Each form has been shown to have a few unique benefits. For example, the sulfur component of glucosamine sulfate is critical because sulfur is an essential nutrient for joint tissue. The HCL form on the other hand, is naturally stable and does not require sodium chloride to stabilize it. This means it is a slightly more pure form and delivers a little bit more glucosamine to the body. TRI-ACTA uses both forms to ensure all the advantages that glucosamine has to offer are available.

What is the difference between Glucosamine Sulphate and Glucosamine Hydrochloride?

Research shows that both Glucosamine Sulfate and Glucosamine Hydrochloride are extremely effective products for joint care. There are a few unique benefits to each form.

What should be remembered is that the active ingredient in any glucosamine product is only the glucosamine element and that the hydrochloride or sulphate acid salt is purely a delivery vehicle.

Research suggests that they both fare equally in their actions. The majority of early trials and studies have primarily used glucosamine in its sulphate form, over hydrochloride. This was simply because of availability at the time. Not surprisingly, much of the data on glucosamine is on glucosamine sulphate. Only more recently has glucosamine hydrochloride been researched to a similar extent. The results from several well conducted studies have shown that hydrochloride is as efficient as the sulphate form (Houpt et al, 1999; Qiu et al, 2005; Zang et al, 2007).

However, there are advantages to both forms. The hydrochloride form of glucosamine is more concentrated than the sulphate form because it is naturally stable. Glucosamine sulphate on the other hand, is naturally unstable and requires sodium chloride to stabilize it.

This means you need to consume less HCL to reap the same benefits. 2 g of sulphate would have the same benefit of roughly 1.5 g of HCL. Simply put, because of stability and purity HCL is more efficient in the sense that it delivers the actual amount of glucosamine as stated on the product label.

However, sulfur is needed by the body to produce cartilage, so glucosamine sulphate has important benefits. The sulfur component of glucosamine sulfate is critical because sulfur is an essential nutrient for joint tissue.

TRI-ACTA uses both forms to ensure all the advantages that glucosamine has to offer are available. TRI-ACTA formulas are highly absorbable and provide all the essential nutrients for healthy joint function.

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